王潇，男,汉族，1978年4月生，教授、博士生导师。2008年获中国农业大学微生物学专业博士学位，同年来内蒙古大学生命科学学院任教，主要从事微生物与免疫学方面的教学科研工作，2009年晋升副教授、2015年晋升教授。现任内蒙古大学生命科学学院副院长。

Email：wangxiao@imu.edu.cn

研究方向：微生物与免疫

主要研究领域：

1.微生物感染机理和宿主免疫应答机制；

2.粘膜疫苗设计及免疫保护机理研究；

3.新型佐剂开发及免疫学机理；

4.益生菌活性多糖的功能及作用机制。

主要科研项目：

1. 国家自然科学基金地区基金项目（批准号：31660706），Gamma/detal T细胞在金黄色葡萄球菌乳腺炎中的应答特征和功能研究，2017/01-2020/12。

2. 国家自然科学基金地区基金项目（批准号：31260599），Th17细胞/IL-17在金黄色葡萄球菌感染小鼠乳腺炎症中的作用研究，2013/01-2016/12。

3. 国家自然科学基金地区基金项目（批准号：31060131），左旋咪唑调节树突状细胞诱导TH1型免疫应答的分子机制研究，2011/01-2013/12。

4. 国家自然科学基金青年基金项目（批准号：30901066），奶牛乳房炎金黄色葡萄球菌对乳腺上皮细胞Toll样受体信号通路影响的研究,2010/01-2012/12。

发表文章：

1.Hu Zhongpeng, Du Ruiping, Xiu Lei, Bian Ziyao, Ma Chaomei, Sato Naoto, Hattori Masao, Zhang Haochi, Liang Yanchen, Yu Shuixing, Wang Xiao*. Protective effect of triterpenes of Ganoderma lucidum on lipopolysaccharide-induced inflammatory responses and acute liver injury. Cytokine, 2020, 127: 154917.

2.Zhao Caiquuan; Zhou Jinxiu; Meng Yanqing; Shi Niu; Wang Xiao; Zhou Ming; Li Guangpeng; Yang Yang*.DHA Sensor GPR120 in Host Defense Exhibits the Dual Characteristics of Regulating Dendritic Cell Function and Skewing the Balance of Th17/Tregs. International Journal of Biological Sciences, 2020, 16(3): 374-387.  

3.Xu R H, Xiu Lei, Zhang Y L, Du R P, Wang Xiao*. Probiotic and hepatoprotective activity of lactobacillus isolated from Mongolian camel milk products. Beneficial Microbes, 2019, 10(6): 1-12.

4.Xu Rihua, Aruhan, Xiu Lei, Sheng Shouxin, Liang Yanchen, Zhang Haochi, Liu Yang, Tong He, Du Ruiping, Wang Xiao*. Exopolysaccharides from Lactobacillus buchneri TCP016 Attenuate LPS- and d-GalN-Induced Liver Injury by Modulating the Gut Microbiota . Journal of Agricultural and Food Chemistry, 2019, 67(42): 11627-37.

5.Li, Chunfu; Zhang, Hongliang; Ji, Lina; Wang, Xiao; Wen, Yongjun; Li, Guangpeng; Fu, Zhen F; Yang, Yang* .Deficient Incorporation of Rabies Virus Glycoprotein into Virions Enhances Virus-Induced Immune Evasion and Viral Pathogenicity.Viruses-Basel, 2019, 11(3): 0-218

6.Yubing Fu, Ting Wang, Lei Xiu, Xiaojie Shi, Ziyao Bian, Yongli Zhang, A. Ruhan, Xiao Wang*. Levamisole promotes murine bone marrow derived dendritic cell activation and drives Th1 immune response in vitro and in vivo. International Immunopharmacology .  31 (2016) :57–65.

7.L. Xiu, Y.B. Fu, Y. Deng, X.J. Shi, Z.Y. Bian, A. Ruhan and Xiao Wang*. Deep sequencing-based analysis of gene expression in bovine mammary epithelial cells after Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae infection. Genetics and Molecular Research, 2015, 14 (4): 16948-16965

8.王婷,崔新洁,刘秉春,陶琳,胡庆亮,修磊,王潇.牛白细胞介素-17真核表达载体的构建及在牛乳腺上皮细胞中的表达.华南农业大学学报, 2014, 35(01): 79-85.

9.Wang, Xiaojing，Wang, Yanfeng，Zheng, Xu，Hao, Xiyan，Liang, Yan，Wu, Manlin，Wang, Xiao*，Wang, Zhigang*，Direct Interaction between Ras Homolog Enriched in Brain and FK506 Binding Protein 38 in Cashmere Goat Fetal Fibroblast Cells，Asian-Australasian Journal of Animal Sciences, 2014, 27（12）:1671-1677.

10.Bao, Wenlei，Yin, Jianxin，Liang, Yan，Guo, Zhixin，Wang, Yanfeng，Liu, Dongjun，Wang, Xiao*，Wang,Zhigang，Recombinant Goat VEGF164 Increases Hair Growth by Painting Process on the Skin of Shaved Mouse，Asian-Australasian Journal of Animal Sciences, 2014, 27（9）: 1355-1359.

11.Qingliang Hu，Xinjie Cui，Lin Tao，Lei Xiu，Ting Wang，Xiao Wang*. Staphylococcus aureus Induces Apoptosis in Primary Bovine Mammary Epithelial Cells Through Fas-FADD Death Receptor-Linked Caspase-8 Signaling.DNA AND CELL BIOLOGY, 2014, 33（6）: 388-397.

12.Jing-jing Wu , Rui-ping Du , Min Gao,Yao-qiang Sui ,Xiao Wang*.Identification and characterization of lactic acid bacteria isolated from tomato pomace. Ann Microbiol, 2014, 64(4):1849-1855.

13.Jing-jing Wu, Rui-ping Du, Min Gao,Yao-qiang Sui, Lei Xiu, and Xiao Wang*. Naturally Occurring Lactic Acid Bacteria Isolated from Tomato Pomace Silage. Asian Australas. J. Anim. Sci, 2014, 27(5): 648-657.

14.Xiao Wang*，Lei Xiu，Qiangliang Hu，Xinjie Cui，Bingchun Liu，Lin Tao，Ting Wang， Jingjing Wu，YuanChen，Yan Chen.，Deep sequencing- based transcriptional analysis of bovine mammary epithelial cells gene expression in response to in vitro infection with Staphylococcus aureus stains. Plos One, 2013, 8（12）: 107-117.

15. 崔新洁, 胡庆亮, 李奕平, 陶琳, 修磊,刘秉春,陈媛,王潇.金黄色葡萄球菌诱导牛原代乳腺上皮细胞的凋亡. 中国农业科学, 2013, 46(15): 3212-3219.

16.刘秉春, 崔新洁, 罗新松, 王潇. 核酸疫苗初免-蛋白疫苗加强的免疫策略提高日本血吸虫核酸疫苗免疫效果. 生物工程学报, 2013, 29(06): 814-822.

17.崔新洁, 王婷, 刘秉春, 陶林, 王潇. 牛奶中乳腺上皮细胞的分离培养及鉴定. 生物技术通报, 2013(03): 107-113.

18.王潇, 王志钢, 杜瑞平. 白细胞介素-10分子佐剂增强口蹄疫DNA疫苗黏膜免疫效果研究. 中国农业科学, 2011, 44(14): 3045-3052.

19.Hanqian Xu, Gan Zhao, Zheng Ding, Junpeng Wang, Xiao Wang, Bin Wang CD40-expressing plasmid induces anti-CD40antibody and enhances immune responses to DNA vaccination. THE JOURNAL OF GENE MEDICINE. 2010 12（1）: 97-106

20.Zhao, G；Jin, H；Li, J；Su, B；Du, X；Kang, Y；Wang, X；Wang, B ，PyNTTTGT protype oligonucleotide IMT504, a novle effective adjuvant of FMDV DNA vaccine. Viral immunology. 2009, 28(2): 136-138

21. Baowei Shu， Junpeng Wang， Xiao Wang ， Bin Wang， The adjuvant effects of cytokine IL-6 and TNF-α on immune responses to FMDV DNA vaccination and DCs maturation. Vaccine. 2008, 26, 5111-5122

22. Xiao Wang,  Huali Jin,  Xiaogang Du,  Chun Cai,  Yang Yu,  Gan Zhao and Bin Wang, The protective efficacy against Schistosoma japonicum by immunization with DNA vaccine and levamisole as adjuvant in mice. Vaccine. 2008, 26, 1832-1845.

23.Xiao Wang, Xinyu Zhang, Youming Kang and Bin Wang, Interleukin- 15 Enhance DNA Vaccine Elicited Mucosal and Systemic Immunity against Foot and Mouth Disease Virus, Vaccine. 2008, 26, 5135-5143.

24. Huali Jin, Xiao Wang, Yang Yu, Lin Zhao, Youmin Kang and Bin Wang, Enhancement of FMDV-Specific Protective Immune Responses by Vaccination with DNA Vaccine Expressing Viral-Like-Particle, Viral Immunol. 2007, 20, 429 - 440.

获奖情况：

2018年入选内蒙古自治区“草原英才”工程青年创新创业人才

2018年获内蒙古自治区高等教育教学成果一等奖（第四完成人）

2013年入选内蒙古自治区教育厅“青年科技英才支持计划——领军人才”

2013年获内蒙古自治区高等学校“教坛新秀”称号

2013年获内蒙古自治区高等教育教学成果二等奖（第四完成人）