吴宝江，博士，副研究员，硕士生导师。2020年以“学术骨干”层次引进内蒙古大学。主要从事哺乳动物新型干细胞研究、蒙古高原地区动物遗传资源收集保存、哺乳动物卵子成熟和早期胚胎发育的表观遗传调控机制研究。近几年，关于小鼠新型干细胞相关研究成果发表在Stem Cell Reports、Cell Research、Nature Cell Biology和Cell Cycle等学术期刊上。目前担任内蒙古生物工程学会理事，内蒙古细胞生物学会会员。

E-mail: wubj@imu.edu.cn

主要研究方向：

1. 哺乳动物新型干细胞诱导和定向分化研究

2. 卵子成熟和早期胚胎发育的表观遗传调控机制研究

3. 蒙古高原地区动物遗传资源收集保存

主持的科研项目：

1. 内蒙古自治区科技重大专子课题，以干细胞为基础的“动物人造胚胎”技术研究，2020.01-2022.12。

2. 内蒙古大学高层次引进人才科研启动项目，2021.01-2023.12。

学习和工作经历：

2020.08-至今：内蒙古大学生命科学学院，特聘副研究员，硕士生导师；

2018.07-2020.07：内蒙古赛科星家畜种业与繁育生物技术研究院，研发主管；

2015.09-2018.06：南京农业大学，博士；

2010.04-2015.08：内蒙古赛科星繁育生物技术（集团）股份有限公司，研发员；

2007.09-2010.03：南京农业大学，硕士；

2003.09-2007.07：内蒙古农业大学，学士。

代表性论文和专利：

(1) Baojiang Wu^#, Yunxia Li^#, Bojiang Li^#, Baojing Zhang^#, Yanqiu Wang, Lin Li, Junpeng Gao, Yuting Fu, Shudong Li, Chen Chen, M. Azim Surani, Fuchou Tang, Xihe Li*, Siqin Bao*. DNMTs play an important role in maintaining the pluripotency of leukemia inhibitory factor dependent embryonic stem cells. Stem Cell Reports, 2021, 16(3):582-596.

(2) Baojiang Wu^#, Lin Li^#, Bojiang Li, Junpeng Gao, Yanglin Chen, Mengyi Wei, Zhiqing Yang, Baojing Zhang, Shudong Li, Kexin Li, Changshan Wang, M. Azim Surani, Xihe Li, Fuchou Tang*, Siqin Bao*. Activin A and BMP4 signaling expands potency of mouse embryonic stem cells in serum-free media. Stem Cell Reports, 2020, 14(2): 241-255.

(3) Siqin Bao, WC Tang, Baojiang Wu, Shinseog Kim, Jingyun Li, Lin Li, Toshihiro Kobayashi, Caroline Lee, Yanglin Chen, Mengyi Wei, Shudong Li, Sabine Dietmann, Fuchou Tang, Xihe Li*, M Azim Surani*. Derivation of hypermethylated pluripotent embryonic stem cells with high potency. Cell Research, 2018, 28(1): 22-34.

(4) Zhenhua Hu, Dennis Eng Kiat Tan, Gloryn Chia, Haihan Tan, Hwei Fen Leong, Benjamin Jieming Chen, Mei Sheng Lau, Kelly Yu Sing Tan, Xuezhi Bi, Dongxiao Yang, Ying Swan Ho, Baojiang Wu, Siqin Bao, Esther Sook Miin Wong, Wee-Wei Tee*. Maternal factor NELFA drives a 2C-like state in mouse embryonic stem cells. Nature Cell Biology, 2020, 22(2): 175-186.

(5) Yanglin Chen^#, Baojiang Wu^#, Li Zheng, Caixia Wu, Mengyi Wei, Chen Chen, Xihe Li*, Siqin Bao*. Induction and maintenance of specific multipotent progenitor stem cells synergistically mediated by Activin A and BMP4 signaling. Journal of Cellular Physiology, 2020, 235(11): 8640-8652.

(6) Baojiang Wu, Lixia Zhao, Chengcheng Zhu, Yanglin Chen, Mengyi Wei, Siqin Bao, Shaochen Sun*, Xihe Li*. Altered apoptosis/autophagy and epigenetic modifications cause the impaired postimplantation octaploid embryonic development in mice. Cell Cycle, 2017, 16(1): 82-90.

(7) Baojiang Wu, Hongyan Xue, Liping Chen, Yanfeng Dai, Jitong Guo, Xihe Li*. Effect of PMSG/hCG on mouse superovulated embryonic development. Journal of Integrative Agriculture, 2013,12(6): 1066-1072.

(8) 包斯琴, 吴宝江, 李喜和. 小鼠或人类的全能性干细胞quteASCs诱导及培养建系方法, 2020.03.10, 中国, 专利号ZL201611094945 .X.