主持科研项目：

1. 国家自然科学基金，2024.01-2026.12

2. 国家自然科学基金，2022.01-2025.12

3. 内蒙古自治区高等学校青年科技英才支持计划，2022.01-2024.12

4. 内蒙古自治区自然科学基金，2021.01-2023.12

5. 内蒙古自治区高等学校科学研究重点项目，2021.01-2023.12

6. 内蒙古自治区科技重大专项子课题，2019.01-2021.12

以主要参加人参与科研项目：

1. 内蒙古自治区科技计划项目（子课题负责人），2021.01-2025.12

2. 国家自然科学基金项目，2019.1-2022.12

3. 国家重点研发计划，2017.7-2020.12

4. 国家自然科学基金项目，2014.1-2017.12

5. 973计划，2011.1-2014.12

发表代表性论文（通讯作者/第一作者）：

1. Lei YX, Liu Y, Xing LH, Wu YJ, Wang XY, Meng FH, Lou YN, Ma ZG, Yuan L and Yu SX. The pseudokinase MLKL contributes to host defense against Streptococcus pluranimalium infection by mediating NLRP3 inflammasome activation and extracellular trap formation. Virulence. 2023 Dec; 14 (1): 2258057.

2. Guo ZX, Ma YZ, Jia ZB, Wang LP, Lu XY, Chen YH, Wang YF, Hao HF, Yu SX and Wang ZG. Crosstalk between integrin/FAK and Crk/Vps25 governs invasion of bovine mammary epithelial cells by S. agalactiae. iScience. 2023 Oct 20; 26 (10): 107884.

3. Liu Y, Liang J, Li JW, Xing LH, Li FX, Wang N, Wu YJ, Ma YZ, Xing ZR, Jiang X, Zhang XY, Lei ZX, Wang X and Yu SX. Phagocyte extracellular traps formation contributes to host defense against Clostridium perfringens infection. Cytokine. 2023 Sep; 169: 156276.

4. Liu Y, Lei YX, Li JW, Ma YZ, Wang XY, Meng FH, Wu YJ, Wang N, Liang J, Zhao CQ, Yang Y, Chen GX and Yu SX. G protein-coupled receptor 120 mediates host defense against clostridium perfringens infection through regulating NOD-like receptor family pyrin domain-containing 3 inflammasome activation. J Agric Food Chem. 2023 May 10; 71 (18): 7119-7130.

5. Liu Y, Xing LH, Li FX, Wang N, Ma YZ, Li JW, Wu YJ, Liang J, Lei YX, Wang XY, Meng FH, Yang YJ, Li GP, Wang X and Yu SX. Mixed lineage kinase-like protein protects against Clostridium perfringens infection by enhancing NLRP3 inflammasome-extracellular traps axis. iScience. 2022 Sep 12; 25 (10): 105121.

6. Hu ZP, Du RP, Xiu L, Bian ZY, Ma CM, Satoc N, Hattoric M, Zhang HC, Liang YC, Yu SX and Wang X. Protective effect of triterpenes of Ganoderma lucidum on lipopolysaccharide-induced inflammatory responses and acute liver injury. Cytokine. 2020 Mar; 127: 154917.

7. Chen W, Yu SX, Zhou FH, Zhang XJ, Gao WY, Li KY, Liu ZZ, Han WY and Yang YJ. DNA sensor IFI204 contributes to host defense against Staphylococcus aureus infection in mice. Front Immunol. 2019 Mar 18; 10: 474.

8. Yu SX, Chen W, Liu ZZ, Zhou FH, Yan SQ, Hu GQ, Qin XX, Zhang J, Ma K, Du CT, Gu JM, Deng XM, Han WY and Yang YJ. Non-hematopoietic MLKL protects against salmonella mucosal infection by enhancing inflammasome activation. Front Immunol. 2018 Feb 2; 9: 119.

9. Yu SX, Zhou FH, Chen W, Jiang GM, Du CT, Hu GQ, Liu ZZ, Yan SQ, Gu JM, Deng XM, Lin TJ, Duan EK and Yang YJ. Decidual stromal cell necroptosis contributes to Polyinosinic-Polycytidylic Acid-triggered abnormal murine pregnancy. Front Immunol. 2017 Aug 2; 8: 916.

10. Yu SX, Chen W, Hu XZ, Feng SY, Li KY, Qi S, Lei QQ, Hu GQ, Li N, Zhou FH, Ma CY, Du CT and Yang YJ. Liver X receptors agonists suppress NLRP3 inflammasome activation. Cytokine. 2017 Mar; 91: 30-37.

11. Yu SX, Du CT, Chen W, Lei QQ, Li N, Qi S, Zhang XJ, Hu GQ, Deng XM, Han WY and Yang YJ. Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression. Sci Rep. 2015 Dec 11; 5: 17935.

12. 于水星, 雷倩倩, 张晓静, 李宁, 杜崇涛, 戚帅, 胡桂秋, 周敏, 宋佩烜, 韩文瑜, 陈巍, 杨勇军. 京尼平抑制细菌鞭毛蛋白引起的小鼠肺炎. 畜牧与兽医. 2015; 47(4): 96-99.