承担的科研项目：

1. 国家自然科学基金委员会，青年科学基金项目，基于CRISPR-Cas9高通量筛选技术的人多能干细胞向滋养层细胞分化机制研究，2023-01-01至2025-12-31，在研，主持

2. 国家农业农村部科技发展中心，“科技创新2030—重大项目”，抗逆抗病高产牛新品种设计与培育，2023-09-01至2025-12-31，在研，子课题主持人

3. 国家农业农村部科技发展中心，“科技创新2030-重大项目”，重要农业生物全基因组选择和畜禽干细胞育种技术创新与应用，2023-12-01至2025-12-31，在研，子课题主持人

4. 广东省基础与应用基础研究基金委员会，区域联合基金-青年基金项目，GRHL2控制的滋养层细胞分化机制研究，2021-10至2024-09，在研，主持

5. 内蒙古国家乳业技术创新中心，科技兴蒙项目，奶牛、奶羊性别控制基因编辑细胞系建立关键技术研究，2023-08-01至2026-6-30，在研，主持

发表的代表性科研论文:（#同等贡献，*通讯作者）

1. Chen Y^#, Ye X^#, Zhong Y^#, Kang X^#, Tang Y, Zhu H, Pang C, Ning S, Liang S, Zhang F, Li C, Li J, Gu C, Cheng Y, Kuang Z, Qiu J, Jin J, Luo H, Fu M, Hui HX, Li L, Ruan D, Liu P, Chen X, Sun L, Ai S, Gao X. SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements. Dev Cell. 2024 Apr 5: S1534-5807(24)00193-X.

2. Zhang F, Pang C, Zhu H, Chen Y*. Timely stimulation of early embryo promotes the acquisition of pluripotency. Cytometry A. 2022 Aug;101(8):682-691.

3. Wei M^#, Chen Y^#, Zhao C, Zheng L, Wu B, Chen C, Li X, Bao S. Establishment of Mouse Primed Stem Cells by Combination of Activin and LIF Signaling. Front Cell Dev Biol. 2021 Aug 5;9:713503.

4. Chen Y^#, Wu B^#, Zheng L, Wu C, Wei M, Chen C, Li X, Bao S. Induction and maintenance of specific multipotent progenitor stem cells synergistically mediated by Activin A and BMP4 signaling. J Cell Physiol. 2020 Nov;235(11):8640-8652.

5. Cao S, Gao X, Liu F, Chen Y, Na Q, Meng Q, Shao P, Chen C, Song Y, Wu B, Li X, Bao S. Derivation and characteristics of induced pluripotent stem cells from a patient with acute myelitis. Front Cell Dev Biol. 2023 Jul 14;11:1172385.

6. Zhao L, Gao X, Zheng Y, Wang Z, Zhao G, Ren J, Zhang J, Wu J, Wu B, Chen Y, Sun W, Li Y, Su J, Ding Y, Gao Y, Liu M, Bai X, Sun L, Cao G, Tang F, Bao S, Liu P, Li X. Establishment of bovine expanded potential stem cells. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2018505118.

7. Bao S, Tang WW, Wu B, Kim S, Li J, Li L, Kobayashi T, Lee C, Chen Y, Wei M, Li S, Dietmann S, Tang F, Li X, Surani MA. Derivation of hypermethylated pluripotent embryonic stem cells with high potency. Cell Res. 2018 Jan;28(1):22-34.

8. Liu BC, Liu FY, Gao XY, Chen YL, Meng QQ, Song YL, Li XH, Bao SQ. Global Transcriptional Analyses of the Wnt-Induced Development of Neural Stem Cells from Human Pluripotent Stem Cells. Int J Mol Sci. 2021 Jul 12;22(14):7473.

9. Wu B, Li L, Li B, Gao J, Chen Y, Wei M, Yang Z, Zhang B, Li S, Li K, Wang C, Surani MA, Li X, Tang F, Bao S. Activin A and BMP4 Signaling Expands Potency of Mouse Embryonic Stem Cells in Serum-Free Media. Stem Cell Reports. 2020 Feb 11;14(2):241-255.

10. 陈杨林, 刘悦石, 李喜和, & 包斯琴. (2017). 小鼠上胚层多能干细胞研究进展. 中国细胞生物学学报, 39(7), 8.