项目主持情况:
(1)国家自然科学基金青年项目,82301806,SRSF1在小鼠精子发生过程中功能与作用机制的研究, 2024/01 - 2026/12,30万,在研,主持;
(2)广东省自然科学基金项目,2021A1515111118,SRSF2在小鼠精子发生过程中功能与作用机制的研究, 2021/10 - 2024/09,10万,在研,主持。
发表论文情况(#共同第一作者,*共同通讯作者):
1. Lei W. L., Han F., Hu M. W., Liang Q. X., Meng T. G., Zhou Q., Ouyang Y. C., Hou Y., Schatten H., Wang Z. B., and Sun Q. Y. Protein phosphatase 6 is a key factor regulating spermatogenesis[J]. Cell Death and Differentiation, 2020, 27(6): 1952-1964. (IF=15.828, 生物学1区)
2. Lei, W. L#., Du, Z#., Meng, T. G#., Su, R#., Li, Y. Y., Ning, Y., Hou, G., Schatten, H., Wang, Z. B., Han, Z., Sun, F*., Qian, W. P*., Liu, C*., Sun, Q. Y*. SRSF2 is required for mRNA splicing during spermatogenesis[J]. BMC Biology, 2023. (IF=5.399, 生物学1区)
3. Lei W. L., Li Y. Y., Meng T. G., Ning Y., Sun S. M., Zhang C. H., Gui Y., Wang Z. B., Qian W. P., and Sun Q. Y. Specific deletion of protein phosphatase 6 catalytic subunit in Sertoli cells leads to disruption of spermatogenesis[J]. Cell Death & Disease, 2021, 12(10): 883. (IF=9.696, 生物学1区)
4. Lei, W. L#., Li, Y. Y#., Du, Z#., Su, R#., Meng, T. G., Ning, Y., Hou, G., Schatten, H., Wang, Z. B., Han, Z., Sun, F*., Qian, W. P*., Liu, C*., Sun, Q. Y*. SRSF1-mediated alternative splicing is required for spermatogenesis. International Journal of Biological Sciences, 2023, 19(15), 4883-4897. (IF=9.200, 生物学2区)
5. Lei W. L., Li Y. Y., Hou Y., Liu C., Qian W. P., Sun Q. Y., and Zhang C. H. Toxic effects of patulin on mouse oocytes and its possible mechanisms[J]. Toxicology, 2021, 153013. (IF=4.571, 药学2区)
6. Lei W. L., Qian W. P., and Sun Q. Y. Critical Functions of PP2A-Like Protein Phosphotases in Regulating Meiotic Progression[J]. Frontiers in Cell and Developmental Biology, 2021, 9(363). (IF=6.081, 生物学2区)
7. Meng T. G#., Lei W. L#., Lu X., Liu X. Y., Ma X. S., Nie X. Q., Zhao Z. H.,Li Q. N., Huang L., Hou Y., Ouyang Y. C., Li L., Tang T. S., Schatten H., Xie W., Gao S. R., Ou X. H., Wang Z. B., and Sun Q. Y. Maternal EHMT2 is essential for homologous chromosome segregation by regulating Cyclin B3 transcription in oocyte meiosis[J]. International Journal of Biological Sciences, 2022, 18(11): 4513-4531.(#共同一作)(IF=9.200, 生物学2区)
8. Meng T. G#., Lei W. L#., Li J., Wang F., Zhao Z. H., Li A., Wang Z. B., Sun Q. Y., and Ou X. H. Degradation of Ccnb3 is essential for maintenance of MII arrest in oocyte[J]. Biochemical and Biophysical Research Communications, 2020, 521(1): 265-269. (#共同一作)(IF=3.575, 生物学4区)