项目主持情况：

1. 国家自然科学基金青年基金项目，项目号31700070，课题名称：新型调控因子RsdA在真菌次级代谢及发育中的功能研究；执行期限：2018年1月至2020年12月，经费24万元，结题，主持

2. 国家重点研发计划（科技部）- 合成生物学专项，项目号2018YFA0900701，任务名称：真核启动子及转录因子元器件库的挖掘及适配性研究；所属课题： 调控元器件的创制与功能表征；所属项目: 生物元器件标准化设计组装与应用研究；执行期限：2019年7月 至 2024年6月，经费50万元，结题，主持 （子课题负责人）

3. 内蒙古大学"骏马计划"B2高层次人才项目，2024年9月至2027年9月，120万，在研，主持

发表论文情况（^#共同第一作者，*共同通讯作者）：

【第一作者及通讯作者论文】

1. P. Zhang^#, G. Wu^#, S. C. Heard, C. Niu, S. A. Bell, F. Li, Y. Ye, Y. Zhang, J. M. Winter. Identification and Characterization of a Cryptic Bifunctional Type I Diterpene Synthase Involved in Talaronoid Biosynthesis from a Marine-Derived Fungus. Organic Letter 09/2022; 24 (38), 7037-7041. (Highlighted by Natural Product Reports, Hot off the press. DOI: 10.1039/D2NP90043B)

2. J. Zhang^#, P. Zhang^#, G. Zeng, G. Wu, L. Qi, G. Chen, W. Fang, W. B. Yin. Transcriptional Differences Guided Discovery and Genetic Identification of Coprogen and Dimerumic Acid Siderophores in Metarhizium robertsii. Frontiers in Microbiology 11/2021; 12:783609.

3. P. Zhang, S. Zhou, G. Wang, Z. An, X. Liu, K. Li, W.B. Yin*. Two transcription factors cooperatively regulate DHN melanin biosynthesis and development in Pestalotiopsis fici. Molecular Microbiology 08/2019; 112(2):649-666.

4. R. Li, Z. Li, K. Ma, G. Wang, W. Li, H. Liu, W. B. Yin*, P. Zhang*, X. Liu*. Strategy for efficient cloning of biosynthetic gene cluster from fungi. SCIENCE CHINA-Life Sciences 06/2019; 62 (8), 1087-1095.

5. S. Zhou^#, P. Zhang^#, H. Zhou, X. Liu, S. M. Li, L. Guo, K. Li, W. B. Yin. A new regulator RsdA mediating fungal secondary metabolism has a detrimental impact on asexual development in Pestalotiopsis fici. Environmental Microbiology 01/2019; 21(1):416-426.

6. G. Zeng^#, P. Zhang^#, Q. Zhang^#, H. Zhao, Z. Li, X. Zhang, C. Wang, W. B. Yin, W. Fang. Duplication of a Pks gene cluster and subsequent functional diversification facilitate environmental adaptation in Metarhizium species. PLoS Genetics 06/2018; 14(6).

7. P. Zhang, X. Wang, A. Fan, Y. Zheng, X. Liu, S. Wang, H. Zou, B. R. Oakley, N. P. Keller, W. B. Yin. A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici. Molecular Microbiology 05/2017; 105(3). (Highlighted by Nature Reviews Microbiology 2019,17,167-180)

8. S. Tan^#, P. Zhang^#, W. Xiao, B. Feng, L. Y. Chen, S. Li, P. Li, W. Zhao, X. Qi, L. P. Yin. TMD1 domain and CRAC motif determine the association and disassociation of MxIRT1 with detergent‐resistant membranes. Traffic 11/2018; 19 (2), 122-137.

9. J. Feng^#, P. Zhang^#, Y. Cui, K. Li, X. Qiao, Y.T. Zhang, S. M. Li, R. J. Cox, B. Wu, M. Ye, W.B. Yin. Regio- and Stereospecific O-Glycosylation of Phenolic Compounds Catalyzed by a Fungal Glycosyltransferase from Mucor hiemalis. Advanced Synthesis & Catalysis 02/2017; 359(6).

10. P. Zhang, S. Tan, J. O. Berry, P. Li, Na Ren, S. Li, G. Yang, W. Wang, X. Qi, L. P. Yin. An Uncleaved Signal Peptide Directs the Malus xiaojinensis Iron Transporter Protein MxIRT1 into the ER for the PM Secretory Pathway. International Journal of Molecular Sciences 11/2014; 15(11).

【合作论文】

11. H. Gao, L. Zhou, P. Zhang, Y. Wang, X. QIan, Y. Liu, G. Wu. Filamentous Fungi-Derived Orsellinic Acid-Sesquiterpene Meroterpenoids: Fungal Sources, Chemical Structures, Bioactivities and Biosynthesis. Planta Medica 05/2023; DOI: 10.1055/a-2099-4932

12. Z. Liu, W. Li, P. Zhang, Y. Sun, W. B. Yin. Heterologous production of bioactive xenoacremone analogs in Aspergillus nidulans. Chinese Journal of Natural Medicines 06/2023; 21 (6), 1-7

13. Z. Liu, W. Li, P. Zhang, J. Fan, F. Zhang, C. Wang, S. Li, Y. Sun, S. Chen, W. B. Yin. Tricarbocyclic core formation of tyrosine-decahydrofluorenes implies a three-enzyme cascade with XenF-mediated sigmatropic rearrangement as a prerequisite. Acta Pharmaceutica Sinica B 03/2021.

14. H. Liu, J. Fan, P. Zhang, Y. Hu, X. Liu, S.M. Li, W.B. Yin. New insights into the disulfide bond formation enzymes in epidithiodiketopiperazine alkaloids. Chemical Science 02/2021; 12 (11), 4132-4138

15. X. Xu, J. Feng, P. Zhang, J. Fan, W. B. Yin. A CRISPR/Cas9 Cleavage System for Capturing Fungal Secondary Metabolite Gene Clusters. Journal of Microbiology and Biotechnology 01/2021. 31(0): 1–8

16. K. Ma, P. Zhang, Q. Tao, N. P. Keller, Y. Yang, W. B. Yin, H. W. Liu. Characterization and Biosynthesis of a Rare Fungal Hopane-Type Triterpenoid Glycoside Involved in the Anti-stress Property of Aspergillus fumigatus. Organic Letters 05/2019; 21(9).

17.  魏鹏霖, 张鹏, 李伟, 汪世华, 尹文兵. 黄曲霉分生孢子色素合成基因 pks1 的鉴定及其对生长发育和侵染性的影响. 微生物学报 2019; 59 (5): 965-977.

18. W. Li, Aili Fan, L. wang, P. Zhang, Z.G. Liu, Z. An, W.B. Yin*: Asperphenamate biosynthesis reveals a novel two-module NRPS system to synthesize amino acid esters in fungi. Chemical Science 01/2018; 9(9).

19. Z. Ma, W. Li, P. Zhang, H. Lyu, Y. Hu, W. B. Yin. Rational design for heterologous production of aurovertin-type compounds in Aspergillus nidulans. Applied Microbiology and Biotechnology 11/2017; 102(Pt 12).

20. A. Fan, W. Mi, Z. Liu, G. Zeng, P. Zhang, Y. Hu, W. Fang, W. B. Yin. Deletion of a Histone Acetyltransferase Leads to the Pleiotropic Activation of Natural Products in Metarhizium robertsii. Organic Letters 03/2017; 19(7).

21. G. Wu, H. Zhou, P. Zhang, X. Wang, W. Li, W. Zhang, X. Liu, H. W. Liu, N. P. Keller, Z. An, Wen-Bing Yin. Polyketide Production of Pestaloficiols and Macrodiolide Ficiolides Revealed by Manipulations of Epigenetic Regulators in an Endophytic Fungus. Organic Letters 03/2016; 18(8).

22. S. Li, X. Zhang, X. Zhang, W. Xiao, J. O. Berry, P. Li, S. Jin, S. Tan, P. Zhang, W. Zhao, L. P. Yin. Expression of Malus xiaojinensis IRT1 (MxIRT1) protein in transgenic yeast cells leads to degradation through autophagy in the presence of excessive iron. Yeast 04/2015; 32(7).

23. S. Tan, R. Han, P. Li, G. Yang, S. Li, P. Zhang, W. Wang, W. Zhao, L. P. Yin. Over-expression of the MxIRT1 gene increases iron and zinc content in rice seeds. Transgenic Research 08/2014; 24(1).

24. Naren, P. Zhang, D. Ma, Y. Wang, S. Li, L. Yin. Overexpression of OsDPR, a novel rice gene highly expressed under iron deficiency, suppresses plant growth.  SCIENCE CHINA Life Sciences 12/2012; 55(12):1082-91.

参编情况：

细胞生物学实验技术教程 | 4版，参与编写