具有代表性的科研项目:
1. 国家自然科学基金地区科学基金项目:蛋白激酶SRPK3磷酸化波形蛋白Vimentin损伤妊娠糖尿病胎盘侵袭功能的机制;2022.01-2025.12;34万
2. 国家自然科学基金地区科学基金项目:DPP3通过调节细胞内ROS蓄积促进胃癌增殖的机制研究;2020.01-2023.12;35万
3. 国家自然科学基金地区科学基金项目: scFv-EGFRvIII修饰ADSCs对人胃癌干细胞恶性生物学行为的影响;2016.01-2019.12;44.4万
4. 内蒙古自治区自然科学基金项目:microRNAlet-7b/HMGA2/p16INK4A通路在胃癌的发生发展以及诊疗中的作用探讨;2018.01-2020.12;3万
5. 内蒙古自治区科技计划项目:LNA-siR-TXNIP缓释泵改善妊娠期糖尿病胎盘功能的技术研发;2020.7-2022.12;46万
6. 自治区卫生计生科研计划项目:CD44v8-10在胃癌中竞争性内源RNA调控网络中的角色探讨;2017/12-2019/12;4万
代表性论文:
1.Jin, W (Jin, Wen); Liu, JL (Liu, Jianli); Yang, J (Yang, Jie); Feng, ZQ (Feng, Zongqi); Feng, ZX (Feng, Zhenxing); Huang, N (Huang, Na); Yang, TY (Yang, Tingyu); Yu, L (Yu, Lan) *.Identification of a key ceRNA network associated with ferroptosis in gastric cancer. SCIENTIFIC REPORTS. DOI:10.1038/s41598-022-24402-3 (中科院三区,影响因子为4.997)
2.Wu, ZY (Wu, Zhouying); Huo, X (Huo, Xue); Yang, TY (Yang, Tingyu); Liu, K (Liu, Kun); Wu, T (Wu, Ting); Feng, ZQ (Feng, Zongqi); Wang, M (Wang, Min); Li, F (Li, Feng); Jia, JC (Jia, Jianchao); Zhang, XR (Zhang, Xiaoran); Gao, WM (Gao, Wenming); Yu, L (Yu, Lan)*. CRISPR/Cas9(-3NLS)/sgHMGA2@PDA nanosystem is the potential efficient gene editing therapy for gastric cancer with HMGA2 high expression. FRONTIERS IN ONCOLOGY. DOI: 10.3389/fonc.2022.978533. SEP 2 2022 (中科院二区,影响因子为5.738)
3.Zongqi Feng, Tingyu Yang, Shichao Dong, Ting Wu, Wen Jin, Zhouying Wu, Bingping Wang, Tiantian Liang, Lei Cao and Lan Yu* . Industrially synthesized biosafe vaterite hollow CaCO3 for controllable delivery of anticancer drugs. Materials Today Chemistry. 2022.4.26 (中科院一区TOP 期刊,影响因子为8.301)
4.Zongqi Feng, Tingyu Yang, Tiantian Liang, Zhouying Wu, Ting Wu, Jianbin Zhang and Lan Yu* . Biomineralization of calcium carbonate under amino acid carbon dots and its application in bioimaging. Materials & Design. 2022.3.30(中科院二区TOP 期刊,影响因子为9.419)
5.Zhouying Wu, Min Wang, Feng Li, Feng Wang, Jianchao Jia, Zongqi Feng, Xue Huo, Jie Yang, Wen Jin, Rina Sa, Wenming Gao, Lan Yu*, CDK13-mediated cell cycle disorder promotes the tumorigenesis of HMGA2-high-expressed gastric cancer, Frontiers in Molecular Biosciences, 2021 Aug 26;8:707295. doi: 10.3389/fmolb. (中科院二区,影响因子为5.246)
6. Sarina, Dong Fang Li, Zong Qi Feng, Jie Du, Wen Hua Zhao, Na Huang, Jian Chao Jia, Zhou Ying Wu, Alamusi, Yong Yun Wang, Xiao Li Ji, Lan Yu*. Mechanism of Placenta Damage in Gestational Diabetes Mellitus by Investigating TXNIP of Patient Samples and Gene Functional Research in Cell Line, Diabetes Ther, 2019, Vol. 10, (6) : 2265-2288. (中科院三区,影响因子为2.827)
7.Lan Yu, Xiyun Bian, Chunyan Zhang, Zhouying Wu, Na Huang, Jie Yang, Wen Jin, Zongqi Feng, Dongfang Li, Xue Huo, Ting Wu, Zhongmin Jiang, Xiaozhi Liu, and Dejun Sun. Ginkgolic acid improves bleomycin-induced pulmonary fibrosis by inhibiting SMAD4 SUMOylation. Oxidative Medicine and Cellular Longevity. 2022.5(中科院二区,影响因子为7.31)
8.Lan Yu, Ailan Wang, Tianbao Li, Wen Jin, Geng Tian, Chunmei Yun, Fei Gao, Xiuzhen Fan, Huimin Wang, Huajun Zhang and Dejun Sun A Retrospective and Multicenter Study on COVID-19 in Inner Mongolia: Evaluating the Influence of Sampling Locations on Nucleic Acid Test and the Dynamics of Clinical and Prognostic Indexes. Frontiers in Medicine. 30 March 2022(中科院三区,影响因子为5.093)
9. Lan Yu, Xiaoli Shi, Xiaoling Liu, Wen Jin, Xiaoqin Jia, Shuxue Xi, Ailan Wang, Tianbao Li, Xiao Zhang, Geng Tian and Deiun Jun, Artificial intelligence systems for diagnosis and clinical classification of COVID-19,Frontiers in Microbiology-SystemsMicrobiology. 2021 Jan 27(中科院二区TOP期刊,影响因子为5.640)
10.Yu,L; Li,TB; Gao,L; Wang.B; Chai,J; Shi,XL; Su,RN; Tian,G; Sun,DJ. A Systematic Analysis on COVID-19 Patients in Inner Mongolia Based on Dynamic Monitoring . BIOMED RESEARCH INTERNATIONAL. APR 21 2021(中科院三区,影响因子为3.411)
11.郅慧,武婷,武洲英,俞兰*. 二肽基肽酶家族与恶性肿瘤的研究进展,医学研究杂志,2023.2 177-180
12.马婧,萨日娜,俞兰*. 胎盘滋养层细胞侵袭行为与MMP-2、MMP-9的研究进展,医学研究杂志,2021.12 152-155
13.朱昊,贾剑超,俞兰*. CircRNA在胃癌液体活检中的研究进展,肿瘤防治研究,2021.48(11):1023-1029
14.包萨日娜,孙德俊,俞兰*. 肺部微生态与肺癌的关系,生命的化学,2021,41(01):33-40
15.王永云,俞兰*. 血清胸苷激酶1在胃癌诊疗中的应用研究进展,国际医药卫生导报,2020.4.15 1037-1041
16.王永云,靳文,俞兰*. 胃癌相关基因及靶向治疗的研究进展,医学综述,2020.10 3814-3819
著作:
1.《内分泌科急症与常见病治疗学》,吉林科学技术出版社出版;主编.出版日期:2016年6月.
2.《实用肿瘤综合治疗学》,科学技术文献出版社;主编;出版日期:2016年12月.
3.《临床内分泌代谢病学》,科学技术文献出版社;主编;出版日期:2017年2月.
4.《内分泌代谢性疾病临床研究》,科学技术文献出版社;第一主编:出版日期:2022年7月.